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TPX2 promotes ferroptosis in LPS-induced C28/I2 chondrocytes via NF-B p65-mediated downregulation of GPX4 and SLC7A11

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In addition, several molecules have been studied as an adjuvant therapy, including L-carnitine, CoQ 10 , vitamin E, vine tea polyphenol, cytoprotective agents (ursodeoxycholic acid), and insulin sensitizers (pioglitazone and metformin) (94)

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